Heptabarb

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Heptabarb
Heptabarbital.svg
Systematic (IUPAC) name
5-cyclohept-1-en-1-yl-5-ethylpyrimidine-2,4,6(1H,3H,5H)-trione
Clinical data
Pregnancy cat.
  •  ?
Legal status
  •  ?
Routes Oral[1]
Pharmacokinetic data
Bioavailability 83%[1]
Metabolism Hepatic
Half-life 6.1-11.2 hours[1]
Excretion Renal[1]
Identifiers
CAS number 509-86-4
ATC code N05CA11
PubChem CID 10518
DrugBank DB01354
ChemSpider 10081 YesY
UNII V10R70ML23 YesY
KEGG C17725 YesY
ChEMBL CHEMBL468837 YesY
Synonyms G-475
Chemical data
Formula C13H18N2O3 
Mol. mass 250.294 g/mol
 YesY (what is this?)  (verify)

Heptabarb (INN; Eudan, Medapan, Medomin, Noctyn), also known as heptabarbitone (BAN) or heptabarbital, is a sedative and hypnotic drug of the barbiturate family.[2][3] It was previously used in Europe for the treatment of insomnia from the 1950s onwards, but has since been discontinued.[2][3]

See also[edit]

References[edit]

  1. ^ a b c d Breimer DD, de Boer AG (December 1975). "Pharmacokinetics and relative bioavailability of heptabarbital and heptabarbital sodium after oral administration to man". European Journal of Clinical Pharmacology 9 (2-3): 169–78. doi:10.1007/bf00614014. PMID 9299. 
  2. ^ a b C. R Ganellin; D. J Triggle; F.. Macdonald (1997). Dictionary of pharmacological agents. CRC Press. p. 1003. ISBN 978-0-412-46630-4. Retrieved 26 November 2011. 
  3. ^ a b Index nominum 2000: international drug directory. Taylor & Francis US. 2000. p. 513. ISBN 978-3-88763-075-1. Retrieved 26 November 2011.