Herd immunity (or community immunity) describes a form of immunity that occurs when the vaccination of a significant portion of a population (or herd) provides a measure of protection for individuals who have not developed immunity. Herd immunity theory proposes that, in contagious diseases that are transmitted from individual to individual, chains of infection are likely to be disrupted when large numbers of a population are immune or less susceptible to the disease. The greater the proportion of individuals who are resistant, the smaller the probability that a susceptible individual will come into contact with an infectious individual.
Vaccination acts as a sort of firebreak or firewall in the spread of the disease, slowing or preventing further transmission of the disease to others. Unvaccinated individuals are indirectly protected by vaccinated individuals, as the latter are less likely to contract and transmit the disease between infected and susceptible individuals. Hence, a public health policy of herd immunity may be used to reduce spread of an illness and provide a level of protection to a vulnerable, unvaccinated subgroup. Since only a small fraction of the population (or herd) can be left unvaccinated for this method to be effective, it is considered best left for those who cannot safely receive vaccines because of a medical condition such as an immune disorder, organ transplant recipients, or people with egg allergies.
Herd immunity generally applies only to diseases that are contagious. It does not apply to diseases such as tetanus (which is infectious, but is not contagious), where the vaccine protects only the vaccinated person from disease. Nor does it apply to the IPV poliomyelitis vaccine that protects the individual from viremia and paralytic polio but does not prevent the fecal-oral spread of infection. Herd immunity should not be confused with contact immunity, a related concept wherein a vaccinated individual can 'pass on' the vaccine to another individual through contact.
|Disease||Transmission||R0||Herd immunity threshold|
|^ - R0 is the basic reproduction number, or the average number of secondary infectious cases that are produced by a single index case in completely susceptible population.|
The proportion of immune individuals in a population above which a disease may no longer persist is the herd immunity threshold. Its value varies with the virulence of the disease, the efficacy of the vaccine, and the contact parameter for the population. No vaccine offers complete protection, but the spread of disease from person to person is much higher in those who remain unvaccinated. It is the general aim of those involved in public health to establish herd immunity in most populations. Complications arise when widespread vaccination is not possible or when vaccines are rejected by a part of the population. As of 2009[update], herd immunity is compromised in some areas for some vaccine-preventable diseases, including pertussis and measles and mumps, in part because of parental refusal of vaccination.
A report by the Centers for Disease Control and Prevention analyzed the gastroenteritis hospitalization rate in the USA before (2000 to 2006) and after (2008 to 2010, the transition year 2007 is excluded) the infant rotavirus vaccination program was introduced in 2006. The analysis shows that not only the hospitalization rate among infants has greatly reduced, older children and adults who are not usually vaccinated against rotavirus also see the illness declined significantly. Since the rotavirus vaccine was introduced, the hospitalization due to rotavirus among children under 5 years old has dropped by 80%, those between 5 to 14 years old by 70%, and people over 65 years old by 14%. The decline in people between 14 to 65 years old fell somewhere in between. Rotavirus cases not requiring hospitalization were not measured in this study but greater decline can be reasonably deduced. This report demonstrates that herd immunity incurred by the infant rotavirus vaccination program benefits the rest of the population.
The standard mathematical definition of herd immunity applies only to "well-mixed populations," in which each infected individual is capable of transmitting the disease to any susceptible individual, regardless of social ties or location. More specifically, the relationship between the basic reproduction number R0 and the herd immunity threshold relies on a calculation that is valid only in well-mixed populations. Actual large populations, however, are better described as social networks, in which transmission can occur only between peers and neighbors. The shape of a social network can alter the level of vaccination required for herd immunity, as well as the likelihood that a population will achieve herd immunity. Compared to well-mixed populations, herd immunity in social networks is particularly fragile.
In cyber security
The principles of herd immunity apply to connected devices both on the internet and inside corporate environments; whereby not all devices in a logically routed network need be patched, covered with up to date anti-malware service or on the latest version of an operating system at the same time.
Many organisations have multiple versions of operating system within their networks and whilst there is usually a strategic drive to ensure all devices are updated it is rarely followed in practice. Providing the majority of devices are up to date, should a worm infect a single device through normal methods of compromise it will struggle to propagate further as most devices will have the latest patch, AV engines or operating systems.
By reducing the number of at risk devices within a network, system administrators may reduce the speed at which a worm may propagate. This allows system administrators the opportunity to update large network estates in a controlled manner whilst allowing a slower upgrade/update path for those machines that cannot be updated quickly. This also allows project managers an opportunity to reduce the risk of network compromise through worms by updating their networks in a staggered manner.
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- Knox, Richard (27 August 2013). "Vaccinating Babies For Rotavirus Protects The Whole Family". NPR. Retrieved 3 September 2013.
- Gastanaduy, Paul; Cums, Aaron; Parashar, Umesh; Lopman, Ben (2013). "Gastroenteritis Hospitalizations in Older Children and Adults in the United Sates Before and After Implementation of Infant Rotavirus Vaccination". The Journal of the American Medical Association 310 (8): 851–853. doi:10.1001/jama.2013.170800.
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- "Vaccine vacuum". Harvard Gazette. 2010-07-29.
- Herd immunity lecture slide show
- Mathematical epidemiology information
- Changes In Population Parameters On The Herd Immunity Threshold
- A visual simulation of herd immunity written by Shane Killian and modified by Robert Webb