Hetacillin

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Hetacillin
Clinical data
AHFS/Drugs.com International Drug Names
Pregnancy cat.  ?
Legal status  ?
Identifiers
CAS number 3511-16-8 YesY
ATC code J01CA18
PubChem CID 193260
DrugBank DB00739
ChemSpider 167708 YesY
UNII TN4JSC48CV YesY
KEGG D01074 N
ChEMBL CHEMBL1201116 N
Chemical data
Formula C19H23N3O4S 
Mol. mass 389.46862
SMILES eMolecules & PubChem
 N (what is this?)  (verify)

Hetacillin is a beta-lactam. Hetacillin is a prodrug and it has no intrinsic antibacterial activity, but is converted by the body to ampicillin, which is active against a variety of organisms.

[edit] Administration

Hetacillin is administered orally. The potassium salt, hetacillin potassium, is administered by injection, either intravenously or intramuscularly.

Hetacillin was removed from the market for human use when the discovery was made that it is actually cleaved in the GI tract to formaldehyde and had no benefit to non-ester derivatives (i.e. Ampicillin).


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