The group flew to Geneva, Switzerland in order to feature Collins in the video. The video carries a serious and reflective tone, with the Bone Thugs and Collins walking separately around the city, interpolating between quick flash scenes of the city streets, scenes of a drumming parade, and the members rapping (singing in Collins' case) either inside a train station or at one of several spots outside (mostly accompanied by at least one other member). Emphasizing the difference between Collins and the rappers, his motions are noticeably calmer and less vivid than Bone's.
Bizzy's verse was removed from the video version due to his no longer being in the group at the time.
"Home" was less than well-received in the United States mainstream; in addition to failing to chart on the Billboard Hot 100, Bone collaborating with Collins was ranked #9 on VH1's "Top 20 Least Hip-Hop Moments in History" special. However, the song gained more positive attention overseas, particularly in the United Kingdom, as it peaked at number 19 in the UK's Top 40 charts. Due to the latter, Bone Thugs-n-Harmony decided to name Phil Collins an honorary member under the moniker "Chrome Bone".