Samuel Hopkins
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Samuel Hopkins may refer to:
- Samuel Hopkins (inventor) (1743–1818), American inventor who was awarded the first US patent for a process to refine potash
- Samuel Hopkins (1721–1803), American clergyman who formulated a religious system called Hopkinsism or Hopkinsianism
- Samuel Hopkins (congressman), (1753–1819), United States Congressman from Kentucky
- Samuel I. Hopkins (1843–1914), U.S. Representative from Virginia
- Samuel M. Hopkins (1772–1837), United States Representative from New York
- Lightnin' Hopkins, real name Sam Hopkins, guitarist
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