Huda Y. Zoghbi (born 1955) is a Lebanese-born physician and medical researcher, practicing in the United States.
She was born June 1955 in Beirut and entered medical school at American University of Beirut in 1975. The Lebanese Civil War began during the school year, and she and her brothers were sent by the family, for safety, to join a sister in Texas. When she was not permitted to return to Lebanon, she obtained admission to Meharry Medical College in Nashville, Tennessee in mid-term.
Her residency as a neurological pediatrician brought Rett syndrome to her attention, and she learned molecular genetics from Arthur Beaudet in order to do research on Rett's and other genetic neurological disorders. She is based at Baylor College of Medicine in Houston, Texas, and affiliated with the Howard Hughes Medical Institute.
She had met William Zoghbi when they were medical students in Beirut, and they later married; he teaches cardiology at Baylor.