Human Research Program
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The Human Research Program (HRP) was created in October 2005 at Johnson Space Center (JSC) in response to NASA's desire to move human research project management away from headquarters to JSC and to focus its research investment on investigating and mitigating the highest risks to astronaut health and performance in support of exploration missions. The HRP is an applied research and technology program that investigates and mitigates risks to astronaut health and performance in support of exploration missions and provides countermeasures and technologies for human space exploration.
The goal of the HRP is to provide human health and performance countermeasures, knowledge, technologies and tools to enable safe, reliable and productive human space exploration. The Human Research Program also aims to educate the public on the challenges of human space flight. 
Human Research Roadmap
The Human Research Roadmap (HRR) is a web-based tool that is used to communicate the content of the Integrated Research Plan (IRP). The IRP is utilized to identify the approach and research activities planned to address risks to human health and performance in space which are assigned to specific Elements within the program.
With this tool, users can search for items as gaps associated with a risk, the tasks associated with a given gap, the cross-integration of a task across multiple gaps or risks and deliverables associated with a gap or risk.
Reviews of the accumulated evidence from medical records, space flight operations and research findings are compiled into Evidence Reports. This evidence provides the basis for identifying the highest priority human risks in space exploration, which comprise the risk portfolio within the HRP. It also provides the basis for identifying gaps and tasks in the research plan.
Risks include physiological effects of radiation, low gravity, terrestrial environments as well as unique challenges in medical support, human factors and behavioral health support. Risks are identified in the Program Requirements Document (PRD) and assigned to an Element within HRP to quantify, mitigate or monitor.
For each risk, the HRP Element identifies gaps in knowledge about the risk and the ability to mitigate the risk. The degree of uncertainty in understanding the likelihood, consequence and/or time-frame of a particular risk are the major factors that drive the gaps. Knowledge or mitigation gaps often appear in multiple risks, and many of the specific research tasks address multiple gaps.
Tasks partially or completely close a gap by better defining a risk or developing mitigation strategies to reduce the risk to an acceptable level. In some cases, a task can address multiple gaps across multiple risks.
Each task culminates in a deliverable or other agreed upon end-product such as recommended standards, flight rules, processes, countermeasures and new technology.
There are currently seven elements in the HRP.
International Space Station Medical Project
Space Radiation Program Element
Human Health Countermeasures
Exploration Medical Capability
Behavioral Health and Performance
Space Human Factors and Habitability
Science Management Office
The following experiments serve as Earth-based (terrestrial) analogs for the space flight environment.
Bed Rest Studies
Desert Research and Technology Studies (D-RATS)
Haughton Mars Project - Research Station
NASA Extreme Environment Mission Operations (NEEMO)
Human-Related Altitude Chamber Complex
External Links and Additional Information
Please see the Human Health and Performance in Space Portal, the Human Research Roadmap website or NASA's Human Research Project website for up-to-date information on the risks currently under investigation.
The Life Science Data Archive (LSDA) contains research data from NASA sponsored research.
The Lifetime Surveillance of Astronaut Health (LSAH) is a repository of electronic heath records of all astronauts and mission data which is collected according to the requirements set forth in the Medical Requirements Integration Document (MRID).