Human umbilical vein graft

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A human umbilical vein graft (HUVG) is a specially prepared human umbilical vein that is used as a vascular graft. HUVGs have found use in arteriovenous fistulae[1] (for patients with ESRD undergoing hemodialysis), as an interposition graft between the subclavian artery and pulmonary artery (in the Blalock-Taussig shunt procedure[2]), and for peripheral bypass graft surgery vascular bypass, when the great saphenous vein (the preferred conduit) is unavailable or unusable.

HUVGs for peripheral bypass grafts are second only to the saphenous vein for long-term patency.[3] However, they do have some tendency to form aneurysms and require more delicate handling than synthetic graft material from PETE (Dacron) or PTFE.


  1. ^ Rubio PA, Farrell EM (March 1980). "Modified human umbilical vein graft arteriovenous fistulae as a source of angioaccess in maintenance hemodialysis". Cardiovasc Dis 7 (1): 51–57. PMC 287831. PMID 15216281. 
  2. ^ Leão LE, Andrade JC, Succi JE, et al. (March 1985). "Modified Blalock-Taussig shunt with an umbilical vein graft". Tex Heart Inst J 12 (1): 65–71. PMC 341796. PMID 15227043. 
  3. ^ Neufang A, Espinola-Klein C, Dorweiler B, et al. (August 2005). "Sequential femorodistal composite bypass with second generation glutaraldehyde stabilized human umbilical vein (HUV)". Eur J Vasc Endovasc Surg 30 (2): 176–83. doi:10.1016/j.ejvs.2005.04.026. PMID 15950502. 

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