Hurthle cell
| Hurthle cell | |
|---|---|
| Classification and external resources | |
 Micrograph showing Hurthle cells in a Hurthle cell neoplasm. Pap stain. |
|
| ICD-10 | C73.9 |
| ICD-O: | 8290/0 |
| DiseasesDB | 31956 |
| eMedicine | med/1045 |
| MeSH | D018249 |
A Hürthle cell is a cell in the thyroid that is often associated with Hashimoto's thyroiditis[1] as well as follicular thyroid cancer.
Contents |
[edit] Histology
Hürthle cells are characterized as enlarged epithelial cells with abundant eosinophilic granular cytoplasm as a result of altered mitochondria.[2] They generally stain pink and are prominently found in histological sections of thyroid glands affected with Hashimoto's.
[edit] Clinical significance
A Hürthle cell adenoma is a type of thyroid benign tumor[3] that, in rare cases, has the potential to become malignant[4] and metastasize (Hürthle cell carcinoma). Hürthle cells are also found in Hashimoto's thyroiditis and toxic and nontoxic nodular goiter. Hürthle cells are hypothesized to be of follicular epithelial origin.
[edit] Eponym
It is named for Karl Hürthle.[5][6]
[edit] See also
[edit] References
- ^ "Endocrine Pathology". http://library.med.utah.edu/WebPath/ENDOHTML/ENDO018.html. Retrieved 2009-05-07.
- ^ Aytug, Serhat (June 13, 2006). "Hurthle Cell Carcinoma". eMedicine. http://www.emedicine.com/med/topic1045.htm.
- ^ "Hürthle cell tumor" at Dorland's Medical Dictionary
- ^ Qian L, Pucci R, Castro CY, Eltorky MA (October 2004). "Renal cell carcinoma metastatic to Hürthle cell adenoma of thyroid". Ann Diagn Pathol 8 (5): 305–8. doi:10.1016/j.anndiagpath.2004.07.011. PMID 15494939. http://linkinghub.elsevier.com/retrieve/pii/S1092913404000735.
- ^ synd/2742 at Who Named It?
- ^ M. Askanazy. Pathologisch-anatomische Beiträge zur Kenntniss des morbus basedowii, insbesondere uber die dabei auftretende Muskelerkrankkung. Deutsches Archiv für klinische Medicin, Leipzig, 1898, 61:118-186.
[edit] External links
- The Doctor's Doctor at thedoctorsdoctor.com
- Illustration at thyroidmanager.org
- EndocrineWeb at endocrineweb.com
- HKU at hku.hk
- Image at upmc.edu
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
|
|||||||||||||||||||||||||||||||||
 |
This cell biology article is a stub. You can help Wikipedia by expanding it. |
