Hydrastine

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Hydrastine
Hydrastine.PNG
Systematic (IUPAC) name
6,7-dimethoxy-3-(6-methyl-5,6,7,8-tetrahydro[1,3]dioxolo[4,5-g]isoquinolin-5-yl)-2-benzofuran-1(3H)-one
Clinical data
Legal status
?
Pharmacokinetic data
Metabolism Hepatic
Excretion Renal
Identifiers
CAS number 118-08-1 YesY
ATC code None
PubChem CID 197835
ChemSpider 171234 YesY
UNII 8890V3217X YesY
ChEMBL CHEMBL497942 N
Chemical data
Formula C21H21NO6 
Mol. mass 383.395 g/mol
 N (what is this?)  (verify)

Hydrastine is a natural alkaloid which was discovered in 1851 by Alfred P. Durand.[1] Hydrolysis of hydrastine yields hydrastinine, which was patented by Bayer as a haemostatic drug[2] during the 1910s.

It is naturally present in Hydrastis canadensis (thus the name) and other plants of the ranunculaceae family.

References[edit]

  1. ^ American Journal of Pharmacy, 1851: 112 .
  2. ^ Römpp CD, Georg Thieme Verlag, 2006 .