Hydrazides in organic chemistry are a class of organic compounds sharing a common functional group characterized by a nitrogen to nitrogen covalent bond with 4 substituents with at least one of them being an acyl group. The general structure for a hydrazide is (R1=O)R2-N-N-R3R4. A related class of compounds called hydrazines do not carry an acyl group. Important members of this class are sulfonylhydrazides such as p-toluenesulfonylhydrazide which are useful reagents in organic chemistry such as in the Shapiro reaction. This reagent can be prepared by reaction of tosyl chloride with hydrazine.
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- IUPAC, Compendium of Chemical Terminology, 2nd ed. (the "Gold Book") (1997). Online corrected version: (2006–) "Hydrazides".
- IUPAC, Compendium of Chemical Terminology, 2nd ed. (the "Gold Book") (1997). Online corrected version: (2006–) "Hydrazines".
- Lester Friedman; Robert L. Litle; Walter R. Reichle (1960), "p-toluenesulfonylhydrazide", Org. Synth. 40: 93; Coll. Vol. 5: 1055