Hydroxylamine reductase

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hydroxylamine reductase
Identifiers
EC number 1.7.99.1
CAS number 37256-42-1
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / EGO

In enzymology, a hydroxylamine reductase (EC 1.7.99.1) is an enzyme that catalyzes the chemical reaction

NH3 + H2O + acceptor \rightleftharpoons hydroxylamine + reduced acceptor

The 3 substrates of this enzyme are NH3, H2O, and acceptor, whereas its two products are hydroxylamine and reduced acceptor.

This enzyme belongs to the family of oxidoreductases, specifically those acting on other nitrogenous compounds as donors with other acceptors. The systematic name of this enzyme class is ammonia:acceptor oxidoreductase. Other names in common use include hydroxylamine (acceptor) reductase, and ammonia:(acceptor) oxidoreductase. This enzyme participates in nitrogen metabolism. It has 2 cofactors: FAD, and Flavoprotein.

References[edit]

  • Taniguchi H, Mitsui H, Nakamura K and Egami F. "Ann. Acad. Sci. Fenn. Ser. A II 60 (1955) 200". 
  • Walker GC and Nicholas DJD (1961). "Hydroxylamine reductase from Pseudomonas aeruginosa". Biochim. Biophys. Acta 49 (2): 361–368. doi:10.1016/0006-3002(61)90135-4. PMID 13782715. 
  • NJ, Ferguson SJ; Allen, JW; Higham, CW; Koppenhofer, A; Zajicek, RS; Watmough, NJ; Ferguson, SJ (2002). "Cytochrome cd1, reductive activation and kinetic analysis of a multifunctional respiratory enzyme". J. Biol. Chem. 277 (5): 3093–100. doi:10.1074/jbc.M108944200. PMID 11709555.