3-Hydroxypentanoic acid

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3-Hydroxypentanoic acid
3-hydroxypentanoic acid.png
CAS number 10237-77-1
PubChem 107802
ChemSpider 96952 YesY
Jmol-3D images Image 1
Image 2
Molecular formula C5H10O3
Molar mass 118.13 g/mol
Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
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Infobox references

3-Hydroxypentanoic acid, or beta-hydroxypentanoate is a 5-carbon ketone body. It is made from odd carbon fatty acids in the liver and rapidly enters the brain. As opposed to 4-carbon ketone bodies, 3-hydroxypentanoic acid is anaplerotic, meaning it can refill the pool of TCA cycle intermediates. The triglyceride triheptanoin is used clinically to produce beta-hydroxypentanoate.[1]


  1. ^ Renée P. Kinman, Takhar Kasumov, Kathryn A. Jobbins, Katherine R. Thomas, Jillian Adams, Lisa N. Brunengraber, Gerd Kutz, Wolf-Ulrich Brewer, Charles R. Roe, and Henri Brunengraber (2006). "Parenteral and Enteral Metabolism of Anaplerotic Triheptanoin in Normal Rats". Am J Physiol Endocrinol Metab 291 (4): E860–E866. doi:10.1152/ajpendo.00366.2005. PMID 16705058.  Reprint