Hyperphosphatemia

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Hyperphosphatemia
Classification and external resources

Phosphate group chemical structure
ICD-9 275.3
DiseasesDB 20722
eMedicine med/1097
MeSH D054559

Hyperphosphatemia is an electrolyte disturbance in which there is an abnormally elevated level of phosphate in the blood.[1] Often, calcium levels are lowered (hypocalcemia) due to precipitation of phosphate with the calcium in tissues.

Contents

[edit] Signs and symptoms

Signs and symptoms include ectopic calcification, secondary hyperparathyroidism, and renal osteodystrophy.


[edit] Causes

Hypoparathyroidism: In this situation, there are low levels of Parathyroid hormone (PTH). PTH normally inhibits renal reabsorption of phosphate, and so without enough PTH there is more reabsorption of the phosphate.

Chronic renal failure: When the kidneys aren't working well, there will be increased phosphate retention.

Osteomalacia, which may be caused by the insufficient content of vitamin D in the diet, the lack of sunlight, malabsorption or renal disorders.

Drugs: hyperphosphatemia can also be caused by taking oral sodium phosphate solutions prescribed for bowel preparation for colonoscopy in children.

[edit] Treatment

High phosphate levels can be avoided with phosphate binders and dietary restriction of phosphate.

[edit] See also

[edit] References


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