Hypervitaminosis E

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Hypervitaminosis E
Classification and external resources

Tocopherol, or vitamin E.

Hypervitaminosis E is a state of vitamin E toxicity. Because vitamin E can act as an anticoagulant and may increase the risk of bleeding problems, many agencies have set an upper tolerable intake level (UL) for vitamin E at 1,000 mg (1,500 IU) per day.[1] This UL was established due to an increased incidence of hemorrhaging with higher doses of supplemental vitamin E. Doses of vitamin E above the UL can also potentiate the antiplatelet effects of certain drugs such as anti-coagulant medications and aspirin, which can cause life-threatening symptoms in ill patients. Hypervitaminosis E may also counteract vitamin K, leading to a vitamin K deficiency.

Contents

[edit] Symptoms and presentation

  • Blotchy skin
  • Increased bleeding
  • Increased triglycerides
  • Decreased production of thyroid hormones
  • Decreased activity of vitamin K
  • Increased hemorrhaging from aspirin or anti-coagulant medications

[edit] See also

[edit] References

[edit] External links


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