The single was Fats Domino's third release in a row to reach number one on the R&B Best Sellers chart, where it stayed for six weeks. The single also continued Fats Domino's crossover appeal when "I'm Walkin'" peaked at number four on the pop singles chart.  The song was featured in The Blues Brothers movie, during the scene in which the orphanage kids help spread the word of the band's revival concert.
Later in 1957, Ricky Nelson performed the song on an episode of his parents' show, The Adventures of Ozzie & Harriet. Ricky Nelson's version was released as a single, which reached number four on the pop singles chart and number ten on the R&B charts. Nelson's version was released on Verve Records label with the B-side being "A Teenager's Romance". After a couple of Verve singles, Nelson also recorded for Imperial Records, the same label Domino was on at the time.
In 1961, the song re-charted as one of three songs in the "New Orleans Medley" by session drummer Earl Palmer. The record reached #108 in the Music Vendor survey.