ICI-199,441

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ICI-199,441
ICI-199441 structure.png
Systematic (IUPAC) name
2-(3,4-dichlorophenyl)-N-methyl-N-[(1S)-1-phenyl-2-pyrrolidin-1-ylethyl]acetamide
Clinical data
Legal status ?
Identifiers
CAS number 115199-84-3 YesY
ATC code ?
PubChem CID 3082718
ChEMBL CHEMBL38576 N
Chemical data
Formula C21H24Cl2N2O 
Mol. mass 391.333 g/mol
 N (what is this?)  (verify)

ICI-199,441 is a drug which acts as a potent and selective κ-opioid agonist, and has analgesic effects.[1][2]

References[edit]

  1. ^ Costello GF, Main BG, Barlow JJ, Carroll JA, Shaw JS (July 1988). "A novel series of potent and selective agonists at the opioid kappa-receptor". European Journal of Pharmacology 151 (3): 475–8. doi:10.1016/0014-2999(88)90546-8. PMID 2850924. 
  2. ^ Narita M, Kaneko C, Miyoshi K, Nagumo Y, Kuzumaki N, Nakajima M, Nanjo K, Matsuzawa K, Yamazaki M, Suzuki T (April 2006). "Chronic pain induces anxiety with concomitant changes in opioidergic function in the amygdala". Neuropsychopharmacology 31 (4): 739–50. doi:10.1038/sj.npp.1300858. PMID 16123756.