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Inducible T-cell co-stimulator ligand
Symbols ICOSLG ; B7-H2; B7H2; B7RP-1; B7RP1; CD275; GL50; ICOS-L; ICOSL; LICOS
External IDs OMIM605717 MGI1354701 HomoloGene49412 GeneCards: ICOSLG Gene
RNA expression pattern
PBB GE ICOSLG 211199 s at tn.png
More reference expression data
Species Human Mouse
Entrez 23308 50723
Ensembl ENSG00000160223 ENSMUSG00000000732
UniProt O75144 Q9JHJ8
RefSeq (mRNA) NM_001283050 NM_015790
RefSeq (protein) NP_001269979 NP_056605
Location (UCSC) Chr 21:
45.64 – 45.66 Mb
Chr 10:
78.07 – 78.08 Mb
PubMed search [1] [2]

ICOS ligand is a protein that in humans is encoded by the ICOSLG gene.[1][2][3] ICOSLG has also been designated as CD275 (cluster of differentiation 275).


  1. ^ Ishikawa K, Nagase T, Suyama M, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (Dec 1998). "Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro". DNA Res 5 (3): 169–76. doi:10.1093/dnares/5.3.169. PMID 9734811. 
  2. ^ Yoshinaga SK, Zhang M, Pistillo J, Horan T, Khare SD, Miner K, Sonnenberg M, Boone T, Brankow D, Dai T, Delaney J, Han H, Hui A, Kohno T, Manoukian R, Whoriskey JS, Coccia MA (Nov 2000). "Characterization of a new human B7-related protein: B7RP-1 is the ligand to the co-stimulatory protein ICOS". Int Immunol 12 (10): 1439–47. doi:10.1093/intimm/12.10.1439. PMID 11007762. 
  3. ^ "Entrez Gene: ICOSLG inducible T-cell co-stimulator ligand". 

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