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Interleukin 1 family, member 10 (theta)
Symbols IL1F10 ; FIL1-theta; IL-1HY2; IL-38; IL1-theta; IL1HY2
External IDs OMIM615296 MGI2652548 HomoloGene17690 GeneCards: IL1F10 Gene
Species Human Mouse
Entrez 84639 215274
Ensembl ENSG00000136697 ENSMUSG00000046845
UniProt Q8WWZ1 Q8R459
RefSeq (mRNA) NM_032556 NM_153077
RefSeq (protein) NP_115945 NP_694717
Location (UCSC) Chr 2:
113.83 – 113.83 Mb
Chr 2:
24.29 – 24.29 Mb
PubMed search [1] [2]

Interleukin-1 family member 10 is a protein that in humans is encoded by the IL1F10 gene.[1][2][3][4]

The protein encoded by this gene is a member of the interleukin 1 cytokine family. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. This cytokine is thought to participate in a network of interleukin 1 family members to regulate adapted and innate immune responses. Two alternatively spliced transcript variants encoding the same protein have been reported.[4]


  1. ^ Bensen JT, Dawson PA, Mychaleckyj JC, Bowden DW (Dec 2001). "Identification of a novel human cytokine gene in the interleukin gene cluster on chromosome 2q12-14". J Interferon Cytokine Res 21 (11): 899–904. doi:10.1089/107999001753289505. PMID 11747621. 
  2. ^ Taylor SL, Renshaw BR, Garka KE, Smith DE, Sims JE (May 2002). "Genomic organization of the interleukin-1 locus". Genomics 79 (5): 726–33. doi:10.1006/geno.2002.6752. PMID 11991723. 
  3. ^ Nicklin MJ, Barton JL, Nguyen M, FitzGerald MG, Duff GW, Kornman K (May 2002). "A sequence-based map of the nine genes of the human interleukin-1 cluster". Genomics 79 (5): 718–25. doi:10.1006/geno.2002.6751. PMID 11991722. 
  4. ^ a b "Entrez Gene: IL1F10 interleukin 1 family, member 10 (theta)". 

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