ING2

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Inhibitor of growth family, member 2
Protein ING2 PDB 1wes.png
PDB rendering based on 1wes.
Available structures
PDB Ortholog search: PDBe, RCSB
Identifiers
Symbols ING2 ; ING1L; p33ING2
External IDs OMIM604215 MGI1916510 HomoloGene20388 GeneCards: ING2 Gene
RNA expression pattern
PBB GE ING2 205981 s at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 3622 69260
Ensembl ENSG00000168556 ENSMUSG00000063049
UniProt Q9H160 Q9ESK4
RefSeq (mRNA) NM_001564 NM_023503
RefSeq (protein) NP_001555 NP_075992
Location (UCSC) Chr 4:
184.43 – 184.43 Mb
Chr 8:
47.67 – 47.68 Mb
PubMed search [1] [2]

Inhibitor of growth protein 2 is a protein that in humans is encoded by the ING2 gene.[1][2]

This gene is a member of the inhibitor of growth (ING) family. Members of the ING family associate with and modulate the activity of histone acetyltransferase (HAT) and histone deacetylase (HDAC) complexes and function in DNA repair and apoptosis.[2]

References[edit]

  1. ^ Shimada Y, Saito A, Suzuki M, Takahashi E, Horie M (Mar 1999). "Cloning of a novel gene (ING1L) homologous to ING1, a candidate tumor suppressor". Cytogenet Cell Genet 83 (3–4): 232–5. doi:10.1159/000015188. PMID 10072587. 
  2. ^ a b "Entrez Gene: ING2 inhibitor of growth family, member 2". 

Further reading[edit]

External links[edit]


This article incorporates text from the United States National Library of Medicine, which is in the public domain.