IQGAP2

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IQ motif containing GTPase activating protein 2
Available structures
PDB Ortholog search: PDBe, RCSB
Identifiers
Symbol IQGAP2
External IDs OMIM605401 HomoloGene101543 GeneCards: IQGAP2 Gene
RNA expression pattern
PBB GE IQGAP2 203474 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 10788 544963
Ensembl ENSG00000145703 ENSMUSG00000021676
UniProt Q13576 Q3UQ44
RefSeq (mRNA) NM_006633 NM_027711
RefSeq (protein) NP_006624 NP_081987
Location (UCSC) Chr 5:
75.7 – 76 Mb
Chr 13:
95.63 – 95.89 Mb
PubMed search [1] [2]

Ras GTPase-activating-like protein IQGAP2 is an enzyme that in humans is encoded by the IQGAP2 gene.[1][2]

This gene encodes a member of the IQGAP family. The protein contains three IQ domains, one calponin homology domain, one Ras-GAP domain and one WW domain. It interacts with components of the cytoskeleton, with cell adhesion molecules, and with several signaling molecules to regulate cell morphology and motility.[2]

Interactions[edit]

IQGAP2 has been shown to interact with CDC42[1] and RAC1.[1]

References[edit]

Further reading[edit]