ITLN1

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Intelectin 1 (galactofuranose binding)
Identifiers
Symbols ITLN1 ; HL-1; HL1; INTL; ITLN; LFR; hIntL; omentin
External IDs OMIM609873 MGI3057189 HomoloGene111044 GeneCards: ITLN1 Gene
Orthologs
Species Human Mouse
Entrez 55600 16429
Ensembl ENSG00000179914 ENSMUSG00000038209
UniProt Q8WWA0 O88310
RefSeq (mRNA) NM_017625 NM_010584
RefSeq (protein) NP_060095 NP_034714
Location (UCSC) Chr 1:
160.85 – 160.85 Mb
Chr 1:
171.52 – 171.54 Mb
PubMed search [1] [2]

Intelectin-1 also known as the intestinal lactoferrin receptor is a protein that in humans is encoded by the ITLN1 gene.[1][2][3] Intelectin-1 functions both as a receptor for bacterial arabinogalactans[1] and for lactoferrin.[4]

References[edit]

  1. ^ a b Tsuji S, Uehori J, Matsumoto M, Suzuki Y, Matsuhisa A, Toyoshima K, Seya T (Jun 2001). "Human intelectin is a novel soluble lectin that recognizes galactofuranose in carbohydrate chains of bacterial cell wall". J Biol Chem 276 (26): 23456–63. doi:10.1074/jbc.M103162200. PMID 11313366. 
  2. ^ Lee JK, Schnee J, Pang M, Wolfert M, Baum LG, Moremen KW, Pierce M (Feb 2001). "Human homologs of the Xenopus oocyte cortical granule lectin XL35". Glycobiology 11 (1): 65–73. doi:10.1093/glycob/11.1.65. PMID 11181563. 
  3. ^ "Entrez Gene: ITLN1 intelectin 1 (galactofuranose binding)". 
  4. ^ Suzuki YA, Shin K, Lönnerdal B (December 2001). "Molecular cloning and functional expression of a human intestinal lactoferrin receptor". Biochemistry 40 (51): 15771–9. doi:10.1021/bi0155899. PMID 11747454. 

Further reading[edit]