The music video for "I Need You Tonight" was shot at a pub in Hackney, London. It features Professor Green being taken as an idiot by a girl (played by model Carly Baker) who he desperately tries to get the attention of. However he ends up becoming extremely drunk and starts causing chaos in the pub. Drewett also appears in the video along with a cameo appearance from Chase Fontaine.
Having been predicted to debut on the UK Singles Chart at number 1, the single debuted at number 3 on 18 April 2010 behind Scouting for Girls and Usher with "This Ain't a Love Song" and "OMG", respectively. The following week the single fell 3 places to number 6, where it remained for two consecutive weeks. On 9 May 2010, the single fell a further 3 places to number 9, the single spent 4 weeks within the Top 10.
On 15 April 2010, "I Need You Tonight" debuted on the Irish Singles Chart at a #24, marking Professor Green's only single to make an impact on the chart. The following week the single rose to #21 and on its third week in the chart, the single rose to its current peak of #15.
Professor Green has performed this song live feat Ed Drewett, with appearances seen at Live from Studio Five, GMTV, T4 on the Beach and on Professor Green's Tour. Following Drewett's departure from live events, Professor Green has been singing "I Need You Tonight" live on tour and on TV without him. An acoustic version of this song was performed by Green and his backing singers for The Sun (UK) newspaper.