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Not to be confused with Icaridin.
Systematic (IUPAC) name

5-hydroxy-2-(4-methoxyphenyl)-8-(3-methylbut-2-enyl)-7- [(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3-

Clinical data
Legal status
Routes Oral
CAS number 489-32-7 N
ATC code None
PubChem CID 5318997
ChemSpider 4477421 YesY
Chemical data
Formula C33H40O15 
Molecular mass 676.662 g/mol
 N (what is this?)  (verify)

Icariin is a flavonol glycoside, a type of flavonoid. It is the 8-prenyl derivative of kaempferol 3,7-O-diglucoside. The compound is derived from several species of plants belonging to the genus Epimedium, Berberidaceae, which are commonly known as Horny Goat Weed or Yin Yang Huo.[1] Extracts from these plants are reputed to produce aphrodisiac effects, and are commonly used in Chinese herbal medicine to enhance erectile function,[2] as well as for several other indications.


  1. ^ Liu JJ, Li SP, Wang YT (January 2006). "Optimization for quantitative determination of four flavonoids in Epimedium by capillary zone electrophoresis coupled with diode array detection using central composite design". J Chromatogr A 1103 (2): 344–9. doi:10.1016/j.chroma.2005.11.036. PMID 16337210. 
  2. ^ Makarova MN, Pozharitskaya ON, Shikov AN, Tesakova SV, Makarov VG, Tikhonov VP (December 2007). "Effect of lipid-based suspension of Epimedium koreanum Nakai extract on sexual behavior in rats". J Ethnopharmacol 114 (3): 412–6. doi:10.1016/j.jep.2007.08.021. PMID 17890032.