Iclazepam

From Wikipedia, the free encyclopedia
Jump to: navigation, search
Iclazepam
Iclazepam.svg
Systematic (IUPAC) name
7-chloro-1-[2-(cyclopropylmethoxy)ethyl]-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one
Clinical data
Legal status ?
Identifiers
CAS number 57916-70-8
ATC code None
PubChem CID 68777
ChemSpider 62020 YesY
UNII FL061Q6NMC YesY
Chemical data
Formula C21H21ClN2O2 
Mol. mass 368.857
 YesY (what is this?)  (verify)

Iclazepam (Clazepam) is a drug which is a benzodiazepine derivative. It has sedative and anxiolytic effects similar to those produced by other benzodiazepine derivatives, and is around the same potency as chlordiazepoxide.

Iclazepam is a derivative of nordazepam substituted with a cyclopropylmethoxyethyl group on the N1 nitrogen. Once in the body, iclazepam is quickly metabolised to nordazepam and its N-(2-hydroxyethyl) derivative, which are thought to be mainly responsible for its effects.[1]

See also[edit]


References[edit]

  1. ^ Giudicelli JF, Berdeaux A, Idrissi N, Richer C. Clazepam: pharmacokinetics and effects on performance. British Journal of Clinical Pharmacology. 1978 Jan;5(1):65-9.