Prota was born and died in Naples. He taught for many years at the Conservatorio di Sant'Onofrio a Porta Capuana in Naples where two of his students were composers Matteo Capranica and Niccolò Jommelli. He wrote mainly sacred music and produced 3 operas.
- La finta fattucchiera (opera buffa, libretto by Angelo Birini), Spring 1721, Naples, Teatro dei Fiorentini)
- La vedova ingegnosa (intermezzi, libretto by Tommaso Mariani, 12 July 1735, Naples, Teatro S. Bartolomeo)
- La camilla (opera buffa, libretto by Antonio Palomba, 1737, Naples, Teatro Nuovo)
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