Immunoconjugate

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Immunoconjugates are antibodies conjugated (joined) to a second molecule, usually a toxin, radioisotope or label.[1]

These conjugates are used in immunotherapy[citation needed] and to develop monoclonal antibody therapy as a targeted form of chemotherapy[2] when they are often known as antibody-drug conjugates.

When the conjugates include a radioisotope see radioimmunotherapy. When the conjugates include a toxin see immunotoxin.

References[edit]

  1. ^ Goldenberg DM, Sharkey RM (2007). "Novel radiolabeled antibody conjugates". Oncogene 26 (25): 3734–44. doi:10.1038/sj.onc.1210373. PMID 17530026. 
  2. ^ Khandare JJ, Minko T (2006). "Antibodies and peptides in cancer therapy". Critical reviews in therapeutic drug carrier systems 23 (5): 401–35. PMID 17425513. 

Further reading[edit]