Imperatorin
| Imperatorin | |
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9-(3-Methylbut-2-enoxy)-7-furo[3,2-g]chromenone |
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Other names
Ammidin |
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| Identifiers | |
| CAS number | 482-44-0 |
| PubChem | 10212 |
| ChemSpider | 9797  |
| UNII | K713N25C78 |
| KEGG | C09269 |
| ChEMBL | CHEMBL453805 |
| Jmol-3D images | Image 1 |
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| Properties | |
| Molecular formula | C16H14O4 |
| Molar mass | 270.28 g/mol |
 (verify) (what is:  / ?)Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) |
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| Infobox references | |
Imperatorin is a furocoumarin and a phytochemical that has been isolated from Urena lobata L. (Malvaceae), Angelica archangelica,[1] Angelica dahurica,[2] Glehnia littoralis,[3] Saposhnikovia divaricata,[4] Cnidium monnieri,[5] Incarvillea younghusbandii,[6] and Zanthoxylum americanum mill.[7] It is biosynthesized from umbelliferone, a coumarin derivative.[8]
[edit] Isolation
The procedure for the isolation of imperatorin from Urena lobata involves exhaustively extracting under reflux with benzene the air-dried and pulverised roots followed by separation by column chromatography.[9]
[edit] See also
- Psoralen, the parent furocoumarin.
[edit] References
- ^ Sigurdsson S, Ogmundsdottir HM, Gudbjarnason S. (July–August 2004). "Antiproliferative effect of Angelica archangelica fruits.". Zeitschrift für Naturforschung C. 4th 59 (7–8): 523–7. PMID 15813373.
- ^ Xie Y, Zhao W, Zhou T, Fan G, Wu Y. (September–October 2010). "An efficient strategy based on MAE, HPLC-DAD-ESI-MS/MS and 2D-prep-HPLC-DAD for the rapid extraction, separation, identification and purification of five active coumarin components from Radix Angelicae Dahuricae". Phytochemical Analysis 21 (5): 473–82. doi:10.1002/pca.1222. PMID 20931624.
- ^ Liu, M., Shi, X., Yang, W., Liu, S., Wang, N., Shi, R., Qiao, S., Wang, Q. and Wang, Y. (2010-09-27). "Quantitative analysis of nine coumarins in rat urine and bile after oral administration of Radix Glehniae extract by high-performance liquid chromatography-electrospray ionization tandem mass spectrometry". Biochemical Chromatography [Epub ahead of print]: n/a–n/a. doi:10.1002/bmc.1517. PMID 20878664.
- ^ Zhao B, Yang X, Yang X, Zhang L. (June 2010). "Chemical constituents of roots of Saposhnikovia divaricata [Chemical constituents of roots of Saposhnikovia divaricata]" (in Chinese). Zhongguo Zhong yao za zhi. 2nd 35 (12): 1569–72. PMID 20815209.
- ^ Shin, Eunjin; Lee, Chul; Sung, Sang Hyun; Kim, Young Choong; Hwang, Bang Yeon; and Lee, Mi Kyeong. (2010-11-17). "Antifibrotic activity of coumarins from Cnidium monnieri fruits in HSC-T6 hepatic stellate cells". Journal of Natural Medicines. 2nd [Epub ahead of print] (2): 370–374. doi:10.1007/s11418-010-0485-7. PMID 21082271. http://www.springerlink.com/content/uj881g010mt00287/fulltext.pdf. Retrieved 2010-11-27.
- ^ Fu, Y; Bai Y, Dawa Z, Bai B, Ding L. (January 2010). "Chemical constituents of Incarvillea younghusbandii [Chemical constituents of Incarvillea younghusbandii]". Zhongguo Zhong yao za zhi. 2nd 35 (1): 58–62. PMID 20349717.
- ^ Bafi-Yeboa, N. F.; Arnason JT, Baker J, Smith ML. (May 2005). "Antifungal constituents of northern prickly ash, Zanthoxylum americanum mill". Phytomedicine 12 (5): 370–7. doi:10.1016/j.phymed.2003.12.005. PMID 15957372.
- ^ F. M. Dean Naturally Occurring Oxygen Ring Compounds, Butterworths, London, 1963.
- ^ A furocoumarin, Imperatorin isolated from Urena lobata L. (Malvaceae) Keshab Ghosh Molbank 2004, M382 [1] open access publication
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