Imperatorin

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Imperatorin
Imperatorin.png
Identifiers
CAS number 482-44-0 YesY
PubChem 10212
ChemSpider 9797 YesY
UNII K713N25C78 YesY
KEGG C09269 YesY
ChEBI CHEBI:5885 N
ChEMBL CHEMBL453805 YesY
Jmol-3D images Image 1
Properties
Molecular formula C16H14O4
Molar mass 270.28 g/mol
Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
 N (verify) (what is: YesY/N?)
Infobox references

Imperatorin is a furocoumarin and a phytochemical that has been isolated from Urena lobata L. (Malvaceae), Angelica archangelica,[1] Angelica dahurica,[2] Glehnia littoralis,[3] Saposhnikovia divaricata,[4] Cnidium monnieri,[5] Incarvillea younghusbandii,[6] and Zanthoxylum americanum mill.[7] It is biosynthesized from umbelliferone, a coumarin derivative.[8]

Isolation[edit]

The procedure for the isolation of imperatorin from Urena lobata involves exhaustively extracting under reflux with benzene the air-dried and pulverised roots followed by separation by column chromatography.[9]

See also[edit]

References[edit]

  1. ^ Sigurdsson S, Ogmundsdottir HM, Gudbjarnason S. (July–August 2004). "Antiproliferative effect of Angelica archangelica fruits.". Zeitschrift für Naturforschung C. 4th 59 (7–8): 523–7. PMID 15813373. 
  2. ^ Xie Y, Zhao W, Zhou T, Fan G, Wu Y. (September–October 2010). "An efficient strategy based on MAE, HPLC-DAD-ESI-MS/MS and 2D-prep-HPLC-DAD for the rapid extraction, separation, identification and purification of five active coumarin components from Radix Angelicae Dahuricae". Phytochemical Analysis 21 (5): 473–82. doi:10.1002/pca.1222. PMID 20931624. 
  3. ^ Liu, M., Shi, X., Yang, W., Liu, S., Wang, N., Shi, R., Qiao, S., Wang, Q. and Wang, Y. (2010-09-27). "Quantitative analysis of nine coumarins in rat urine and bile after oral administration of Radix Glehniae extract by high-performance liquid chromatography-electrospray ionization tandem mass spectrometry". Biochemical Chromatography. [Epub ahead of print]: n/a–n/a. doi:10.1002/bmc.1517. PMID 20878664. 
  4. ^ Zhao B, Yang X, Yang X, Zhang L. (June 2010). "Chemical constituents of roots of Saposhnikovia divaricata" [Chemical constituents of roots of Saposhnikovia divaricata]. Zhongguo Zhong yao za zhi. 2nd (in Chinese) 35 (12): 1569–72. PMID 20815209. 
  5. ^ Shin, Eunjin; Lee, Chul; Sung, Sang Hyun; Kim, Young Choong; Hwang, Bang Yeon; Lee, Mi Kyeong. (2010-11-17). "Antifibrotic activity of coumarins from Cnidium monnieri fruits in HSC-T6 hepatic stellate cells". Journal of Natural Medicines. 2nd. [Epub ahead of print] (2): 370–374. doi:10.1007/s11418-010-0485-7. PMID 21082271. Retrieved 2010-11-27. 
  6. ^ Fu, Y; Bai Y; Dawa Z; Bai B; Ding L. (January 2010). "Chemical constituents of Incarvillea younghusbandii" [Chemical constituents of Incarvillea younghusbandii]. Zhongguo Zhong yao za zhi. 2nd 35 (1): 58–62. PMID 20349717. 
  7. ^ Bafi-Yeboa, N. F.; Arnason JT; Baker J; Smith ML. (May 2005). "Antifungal constituents of northern prickly ash, Zanthoxylum americanum mill". Phytomedicine 12 (5): 370–7. doi:10.1016/j.phymed.2003.12.005. PMID 15957372. 
  8. ^ F. M. Dean Naturally Occurring Oxygen Ring Compounds, Butterworths, London, 1963.
  9. ^ A furocoumarin, Imperatorin isolated from Urena lobata L. (Malvaceae) Keshab Ghosh Molbank 2004, M382 [1] open access publication