Insulin index

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The Insulin Index is a measure used to quantify the typical insulin response to various foods. The index is similar to the Glycemic Index and Glycemic Load, but rather than relying on blood glucose levels, the Insulin Index is based upon blood insulin levels. This measure can be more useful than either the Glycemic Index or the Glycemic Load because certain foods (e.g., lean meats and proteins) cause an insulin response despite there being no carbohydrates present, and some foods cause a disproportionate insulin response relative to their carbohydrate load.

Holt et al. have noted that the glucose and insulin scores of most foods are highly correlated,[1] but high-protein foods and bakery products that are rich in fat and refined carbohydrates "elicit insulin responses that were disproportionately higher than their glycemic responses." They also conclude that insulin indices may be useful for dietary management and avoidance of non-insulin-dependent diabetes mellitus and hyperlipidemia.

[edit] Explanation of Index

The insulin index shows how much insulin is present in people's blood as a result of a particular food, the glucose index shows how much glucose is present in the blood as a result of a particular food, and the satiety index shows how much a particular food decreases one's propensity to eat more.

Glucose (glycemic) and insulin scores were determined by feeding 1000 kilojoules (239 kilocalories) of the food to the participants and recording the area under the glucose/insulin curve for 120 minutes then dividing by the area under the glucose/insulin curve for white bread. The result being that all scores are relative to white bread. The satiety score was determined by comparing how much food was eaten by participants at a buffet after being fed a fixed number of calories of a particular food while blindfolded (to ensure food appearance was not a factor), then dividing that number by the amount eaten by participants after eating white bread. White bread serves as the baseline of 100. In other words, foods scoring higher than 100 are more satisfying than white bread and those under 100 are less satisfying.

+/- indicate uncertainty in the data. For example 60 +/- 12 means that there's a 95% chance the score is between 60-12 (48) and 60+12 (72), 60 being the highest probability assuming a bell curve. In practice this means that if two foods have large uncertainty and have values close together then you don't really know which score is the higher.

Mean average glucose,[2] insulin[2] and satiety scores[3]
Food Food Type Glucose score Insulin score Satiety score
All-Bran Breakfast Cereal &1000000000000004000000040 ± 7 &1000000000000003200000032 ± 4 &10000000000000151000000151
Porridge Breakfast Cereal &1000000000000006000000060 ± 12 &1000000000000004000000040 ± 4 &10000000000000209000000209
Muesli Breakfast Cereal &1000000000000004300000043 ± 7 &1000000000000004600000046 ± 5 &10000000000000100000000100
Special K Breakfast Cereal &1000000000000007000000070 ± 9 &1000000000000006600000066 ± 5 &10000000000000116000000116
Honeysmacks Breakfast Cereal &1000000000000006000000060 ± 7 &1000000000000006700000067 ± 6 &10000000000000132000000132
Sustain Breakfast Cereal &1000000000000006600000066 ± 6 &1000000000000007100000071 ± 6 &10000000000000112000000112
Cornflakes Breakfast Cereal &1000000000000007600000076 ± 11 &1000000000000007500000075 ± 8 &10000000000000118000000118
Average: Breakfast Cereal &1000000000000005900000059 ± 3 &1000000000000005700000057 ± 3 &10000000000000134000000134
White bread(baseline) Carbohydrate-rich &10000000000000100000000100 ± 0 &10000000000000100000000100 ± 0 &10000000000000100000000100
White Pasta Carbohydrate-rich &1000000000000004600000046 ± 10 &1000000000000004000000040 ± 5 &10000000000000119000000119
Brown pasta Carbohydrate-rich &1000000000000006800000068 ± 10 &1000000000000004000000040 ± 5 &10000000000000188000000188
Grain bread[n 1] Carbohydrate-rich &1000000000000006000000060 ± 12 &1000000000000005600000056 ± 6 &10000000000000154000000154
Brown rice Carbohydrate-rich &10000000000000104000000104 ± 18 &1000000000000006200000062 ± 11 &10000000000000132000000132
French fries Carbohydrate-rich &1000000000000007100000071 ± 16 &1000000000000007400000074 ± 12 &10000000000000116000000116
White rice Carbohydrate-rich &10000000000000110000000110 ± 15 &1000000000000007900000079 ± 12 &10000000000000138000000138
Whole-meal bread[n 2] Carbohydrate-rich &1000000000000009700000097 ± 17 &1000000000000009600000096 ± 12 &10000000000000157000000157
Potatoes Carbohydrate-rich &10000000000000141000000141 ± 35 &10000000000000121000000121 ± 11 &10000000000000323000000323
Average: Carbohydrate-rich &1000000000000008800000088 ± 6 &1000000000000007400000074 ± 8 &10000000000000158556000158.556
Eggs Protein-rich &1000000000000004200000042 ± 16 &1000000000000003100000031 ± 6 &10000000000000150000000150
Cheese Protein-rich &1000000000000005500000055 ± 18 &1000000000000004500000045 ± 13 &10000000000000146000000146
Beef Protein-rich &1000000000000002100000021 ± 8 &1000000000000005100000051 ± 16 &10000000000000176000000176
Lentils Protein-rich &1000000000000006200000062 ± 22 &1000000000000005800000058 ± 12 &10000000000000133000000133
Fish Protein-rich &1000000000000002800000028 ± 13 &1000000000000005900000059 ± 18 &10000000000000225000000225
Baked beans Protein-rich &10000000000000114000000114 ± 18 &10000000000000120000000120 ± 19 &10000000000000168000000168
Average: Protein-rich &1000000000000005400000054 ± 7 &1000000000000006100000061 ± 7 &10000000000000166332999166.333
Apples Fruit &1000000000000005000000050 ± 6 &1000000000000005900000059 ± 4 &10000000000000197000000197
Oranges Fruit &1000000000000003900000039 ± 7 &1000000000000006000000060 ± 3 &10000000000000202000000202
Bananas Fruit &1000000000000007900000079 ± 10 &1000000000000008100000081 ± 5 &10000000000000118000000118
Grapes Fruit &1000000000000007400000074 ± 9 &1000000000000008200000082 ± 6 &10000000000000162000000162
Average: Fruit &1000000000000006100000061 ± 5 &1000000000000007100000071 ± 3 &10000000000000169750000169.75
Peanuts Snack/confectionery &1000000000000001200000012 ± 4 &1000000000000002000000020 ± 5 &1000000000000008400000084
Popcorn Snack/confectionery &1000000000000006200000062 ± 16 &1000000000000005400000054 ± 9 &10000000000000154000000154
Potato chips Snack/confectionery &1000000000000005200000052 ± 9 &1000000000000006100000061 ± 14 &1000000000000009100000091
Ice cream Snack/confectionery &1000000000000007000000070 ± 19 &1000000000000008900000089 ± 13 &1000000000000009600000096
Yogurt Snack/confectionery &1000000000000006200000062 ± 15 &10000000000000115000000115 ± 13 &1000000000000008800000088
Mars Bars Snack/confectionery &1000000000000007900000079 ± 13 &10000000000000122000000122 ± 15 &1000000000000007000000070
Jellybeans Snack/confectionery &10000000000000118000000118 ± 18 &10000000000000160000000160 ± 16 &10000000000000118000000118[n 3]
Average: Snack/confectionery &1000000000000006500000065 ± 6 &1000000000000008900000089 ± 7 &10000000000000100142857100.142857
Doughnuts Bakery product &1000000000000006300000063 ± 12 &1000000000000007400000074 ± 9 &1000000000000006800000068
Croissants Bakery product &1000000000000007400000074 ± 9 &1000000000000007900000079 ± 14 &1000000000000004700000047
Cake Bakery product &1000000000000005600000056 ± 14 &1000000000000008200000082 ± 12 &1000000000000006500000065
Crackers Bakery product &10000000000000118000000118 ± 24 &1000000000000008700000087 ± 12 &10000000000000127000000127
Cookies Bakery product &1000000000000007400000074 ± 11 &1000000000000009200000092 ± 15 &10000000000000120000000120
Average: Bakery product &1000000000000007700000077 ± 7 &1000000000000008300000083 ± 5 &1000000000000008540000085.4
Average: Average &1000000000000006733299967.333 ± 5.667 &1000000000000007250000072.5 ± 5.5 &10000000000000135696957135.696958
Average: ALL &1000000000000006884210068.8421 ± 12.7105 &1000000000000007226315872.263158 ± 9.5 &10000000000000136052631136.052632
Food Food Type Glucose score Insulin score Satiety score
  1. ^ Rye bread containing 47% kibbled rye, Holt et al.
  2. ^ Bread made from whole-meal wheat flour, Holt et al.
  3. ^ the authors of the satiety study [Holt et al.,1995] stated that the amount of jellybeans consumed tended to make participants nauseated which may have produced an erroneous satiety score.

[edit] See also

[edit] References

  1. ^ There Is a Cure for Diabetes: The Tree of Life 21-Day+ Program. Gabriel Cousens, David Rainoshek. North Atlantic Books; January 8, 2008. ISBN 1556436912]
  2. ^ a b Holt, Susanne H.A.; Brand-Miller, Janette Cecile; Petocz, Peter (1996.11.21). written at Human Nutrition Unit. Department of Biochemistry, The University of Sydney; and the School of Mathematical Sciences, The University of Technology, Sydney, Australia. "An insulin index of foods: the insulin demand generated by 1000-kJ portions of common foods" (PDF). the American Journal of Clinical Nutrition (USA: The American Society for Clinical Nutrition, Inc) 66 (5): 1264–1276. 1997 November. http://www.ajcn.org/cgi/reprint/66/5/1264.pdf. Retrieved 2011-06-02. Lay summary – Insulin Index By David Mendosa (2009.10.14). 
  3. ^ Holt, Susanne H.A.; Brand-Miller, Janette Cecile; Petocz, Peter; Farmakalidis, E. (1995). "A satiety index of common foods". European Journal of Clinical Nutrition (Department of Biochemistry, University of Sydney, Australia) 49 (9): 675–690. 1995 September. PMID 7498104. Lay summary – The Satiety Index - What Really Satisfies By David Mendosa (2005.01.10). 
  • Mäkeläinen, H, The effect of β-glucan on the glycemic and insulin index, European Journal of Clinical Nutrition, 6 December 2006
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