Interstate 164 (I-164) is a spur highway of Interstate 64 between that route and U.S. Highway 41 (US 41) in Evansville, Indiana. I-164, also known as the Robert D. Orr Highway, has a total length of 21.24 miles (34.18 km). Requested as an Interstate and approved in 1968, the freeway was opened to traffic on August 2, 1990.
I-164 is signed north–south as it wraps around the east side of the metropolitan area and then east–west as it curves to meet US 41. West of US 41, the freeway becomes Veterans Memorial Parkway, a urban surface arterial which provides a direct connection with Evansville's central business district.
A planned extension of I-69 will utilize much of the existing route of I-164 and eventually create a new international trade corridor from Canada to the Rio Grande Valley. The north end of I-164 connects with the new southern Indiana portion of I-69. Most of I-164, from its northern terminus at I-64/I-69 to a point approximately 1.5 miles (2.4 km) east of US 41, will be eventually designated as I-69.