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Ionomycin free acid.png
CAS number 56092-81-0 YesY
PubChem 6912226
ChemSpider 5288579 N
ChEMBL CHEMBL501617 N, CHEMBL1222121
Jmol-3D images Image 1
Molecular formula C41H72O9
Molar mass 709.00 g mol−1
Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
 N (verify) (what is: YesY/N?)
Infobox references

Ionomycin is an ionophore produced by the bacterium Streptomyces conglobatus.[1] It is used in research to raise the intracellular level of calcium (Ca2+) and as a research tool to understand Ca2+ transport across biological membranes. It is also used to stimulate the intracellular production of the following cytokines; interferon, perforin, IL-2, and IL-4 - usually in conjunction with PMA. These cytokines are important in the inflammatory response.

Commercially, Ionomycin can be obtained as a free acid, or as a Ca2+ salt.


  1. ^ See Ionomycin Calcium salt from Fermentek, manufacturer's product page for ionomycin