Ipsapirone

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Ipsapirone
Ipsapirone.svg
Systematic (IUPAC) name
9,9-dioxo-8-[4-(4-pyrimidin-2-ylpiperazin-1-yl)butyl]-
6-thia-8-azabicyclo[4.3.0]nona-1,3,5-trien-7-one
Clinical data
  • Uncontrolled
Oral
Pharmacokinetic data
Half-life 1.3-2.7 hours
Identifiers
95847-70-4 YesY
None
PubChem CID 56971
IUPHAR ligand 42
ChemSpider 51365 YesY
UNII 6J9B11MN0K YesY
ChEMBL CHEMBL8412 YesY
Chemical data
Formula C19H23N5O3S
401.484 g/mol
 YesY (what is this?)  (verify)

Ipsapirone is a selective 5-HT1A receptor partial agonist of the piperazine and azapirone chemical classes.[1] It has antidepressant and anxiolytic effects.[1] Ipsapitone was studied in 3 placebo contolled trials for depression and continues to be used in research.[2]

See also[edit]

References[edit]

  1. ^ a b Fanelli RJ, Schuurman T, Glaser T, Traber J (1990). "Ipsapirone: a novel anxiolytic and selective 5-HT1A receptor ligand". Progress in clinical and biological research 361: 461–7. PMID 1981264. 
  2. ^ "Azapirones for generalized anxiety disorder.". Cochrane Database Syst Rev. (3): CD006115. Jul 19, 2006. doi:10.1002/14651858.CD006115. PMID 16856115.