Five of its bishops are known:
- John (325)
- Menodorus (451)
- Paul (458)
- George (692)
- Euschemon (878).
The city is mentioned by Hierocles in the sixth century and George of Cyprus in the seventh. It figures in the Notitia Episcopatuum of Anastasius, Patriarch of Antioch in the sixth century, and in the Nova Tactica of the tenth century, as attached to the Patriarchate of Constantinople.
At this period, the Byzantine emperors had taken the province of Isauria from the Patriarchate of Antioch. W. M. Ramsay, following John Sterrett, identifies Irenopolis with Irnebol, of which he does not indicate the exact situation.
- Le Quien, Oriens Christianus, II, 897-900, 1029 sq.
- Asia Minor, London, 1890, p. 365.
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