Most notable of all his accomplishments, Culver is credited for solving a fatal flaw in the Lockheed P-38, which killed several pilots.
A humorous episode during World War II resulted in giving the very secret Lockheed "Advanced Development Projects" division the name "Skunk Works". A phone call to W. A. "Dick" Pulver was misdirected to Irv Culver who answered the phone with "Skonk Works, inside man Culver" and the name stuck!. Another variant of the story relates that the original Skunk Works was located in a circus tent adjacent to the Lockheed plastics fabrication facility which smelled bad and reminded the engineers of the "L'il Abner" comic strip. Reportedly, Culver showed up for work wearing a civil defense gas mask as a gag and when he answered the phone he said "Skonk Works" referring to the cartoon. "Kelly overheard him and chewed out Irv for ridicule: "Culver, you're fired," Kelly roared. "Get your ass out of my tent." Irv Culver showed up for work the next day and Kelly never said a word.Kelly Johnson referred to Culver as "a brilliant designer" in his autobiography 
Culver was interested in a variety of aircraft configurations and developed guidelines for laying out the twist distribution on tailless aircraft. He also helped to design an experimental helicopter, distinguished by a forward-sweeping blade, that was extremely easy to fly. In 1966, Culver, Thomas Hanson and Lance Hook were awarded a patent (US3261407) for a rigid rotor system which set world speed records for Lockheed helicopters and laid the foundation for aerobatic rotorcraft. It earned Culver the Dr. Alexander Klemin Award from the American Helicopter Society.
In recent years, Culver was noted by Dan Armstrong, President of Experimental Soaring Association, for his work with Jim Maupin designing gliders intended to be built by craftsmen from plans. Culver is a well-known aerodynamicist. He published a 13-page paper on the design analysis for the Windrose 15-meter glider that he designed with Maupin.