Isacova is an old village in Orhei County, inhabited mostly by descendants of small land owners from medieval times ("razesi" (razashi) and "mazili"). According to one of the earliest documents mentioning Isacova, in 1645 is set the limit between Isacova and Orhei.
Documente privitoare la târgul şi ţinutul Orheiului, publicate cu un studiu introductiv de Sava Aurel, Institutul de Istorie Naţională din Bucureşti, Bucureşti,1944, LV+561p, B.A.R.: II 234647+; B.C.U. Page 84.