Isoconazole

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Isoconazole
Systematic (IUPAC) name
(RS)-1-[2-[(2,6-Dichlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole
Clinical data
AHFS/Drugs.com International Drug Names
Pregnancy cat.  ?
Legal status  ?
Identifiers
CAS number 27523-40-6
ATC code D01AC05 G01AF07
PubChem CID 3760
ChemSpider 3629
UNII GRI7WFR424 YesY
KEGG D04624
Chemical data
Formula C18H14Cl4N2O 
Mol. mass 416.127 g/mol
SMILES eMolecules & PubChem

Isoconazole is an azole antifungal drug.[1] Nigerian and British medical researchers found that for foot and vaginal infections, isoconazole has a similar effectiveness to clotrimazole.[2][3]

[edit] References

  1. ^ The Merck Index, 12th Edition, 5176
  2. ^ Oyeka, C.A.; Gugnani H.C. (1992). Isoconazole nitrate versus clotrimazole in foot and nail infections due to Hendersonula toruloidea, Scytalidium hyalinum and dermatophytes.. PMID 1302811. 
  3. ^ Cohen, L. (1984). "Single dose treatment of vaginal candidosis: comparison of clotrimazole and isoconazole.". http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1046268. Retrieved 2008-05-23. 


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