Isopropamide

From Wikipedia, the free encyclopedia
Jump to: navigation, search
Isopropamide
Isopropamide.png
Systematic (IUPAC) name
4-amino-N,N-diisopropyl-N-methyl-4-oxo-3,3-diphenylbutan-1-aminium
Clinical data
MedlinePlus a694006
Legal status
  • US: Rx-only, Unscheduled
  • Unscheduled
Routes Oral
Identifiers
CAS number 7492-32-2 N
ATC code A03AB09
PubChem CID 3775
DrugBank DB01625
ChemSpider 3643 YesY
UNII 8B9I31H724 YesY
ChEMBL CHEMBL1201232 N
Chemical data
Formula C23H33N2O1 + 
Mol. mass 353.52092 g/mol
 N (what is this?)  (verify)

Isopropamide is a long-acting anticholinergic drug. It is used in the treatment of peptic ulcers and other gastrointestinal disorders involving hyperacidity (gastrointestinal acidosis) and hypermotility. Chemically, it contains a quaternary ammonium group. It is most often provided as an iodide salt, but is also available as a bromide or chloride salt. It was discovered at Janssen Pharmaceutica in 1954.

References[edit]

  • Seeherman R, Isopropamide iodide: a long-acting anticholinergic, Del Med J. 1957 Oct;29(10):265-9.
  • Boss EG Jr, Buchanan GC, Effect of isopropamide iodide on basal gastric secretion in the human, Gastroenterology. 1957 Nov;33(5):730-6.