According to an interview published in Hit Parader in March 1988, "It's So Easy" is "an account of a time Duff McKagan and West Arkeen, and also the rest of the band, were kinda going through. They didn't have money, but they had a lot of hangers on and girls [they] could basically live off of ... things were just too easy. There's an emptiness; it's so easy."
In an Eddie Trunk interview from 2006, Axl said that Duff and West originally wrote the song as an acoustic "Hippie Ya-Ya" song, and that it was Slash's decision to turn it into a rock song.
There was an original music video made for "It's So Easy", the first ever made from the band; the video features the band playing live in front of a crowd on stage. A heavily edited version of the video was later made for promotional purposes. It was not included on the band's Welcome to the Videos DVD, and as such its content is rare and can only be found on the internet. At the time the video was released, Guns N' Roses were not as popular as they would eventually become, the single was never released in the United States and its video was never accepted by MTV.
"It's So Easy" is one of the band's live staples, performed early in a typical setlist at almost every live performance since 1986. The song was the band's regular show opener after the release of Appetite For Destruction in 1987 and was a frequent opener during the Use Your Illusion Tour in 1991-1993.
Axl Rose has continued to perform the song early in the set since the start of the Chinese Democracy Tour in 2001 up to present day Guns N' Roses tours.
Duff McKagan, the song's primary songwriter, has performed the song in most of his post-Guns N' Roses projects, including the tour in support of his 1993 album Believe In Me. Duff's band, Loaded, have been performing the song since their inception in 1999.