|Area||0.79 sq mi (2 km2)|
|- land||0.79 sq mi (2 km2)|
|- water||0.00 sq mi (0 km2)|
|Density||754.7 / sq mi (291 / km2)|
|- summer (DST)||CDT (UTC-5)|
Iuka is located at (38.617678, -88.788400).
According to the 2010 census, the village has a total area of 0.79 square miles (2.0 km2), all land.
As of the census of 2000, there were 598 people, 219 households, and 169 families residing in the village. The population density was 754.7 people per square mile (292.3/km²). There were 232 housing units at an average density of 292.8 per square mile (113.4/km²). The racial makeup of the village was 98.66% White, 0.17% African American, 0.17% Asian, and 1.00% from two or more races. Hispanic or Latino of any race were 0.84% of the population.
There were 219 households out of which 42.0% had children under the age of 18 living with them, 58.0% were married couples living together, 13.7% had a female householder with no husband present, and 22.8% were non-families. 18.3% of all households were made up of individuals and 12.8% had someone living alone who was 65 years of age or older. The average household size was 2.73 and the average family size was 3.13.
In the village the population was spread out with 31.4% under the age of 18, 7.9% from 18 to 24, 30.4% from 25 to 44, 16.2% from 45 to 64, and 14.0% who were 65 years of age or older. The median age was 34 years. For every 100 females there were 89.8 males. For every 100 females age 18 and over, there were 88.9 males.
The median income for a household in the village was $27,375, and the median income for a family was $29,605. Males had a median income of $30,000 versus $20,417 for females. The per capita income for the village was $11,520. About 13.1% of families and 16.7% of the population were below the poverty line, including 17.1% of those under age 18 and 14.3% of those age 65 or over.
There is a limestone outcropping due southeast of Iuka, IL that is one of the purported locations of Burrows Cave.  In 1982, Russell E. Burrow claimed to have found numerous archeological artifacts in this cave inscribed in Ancient Egyptian and Greek. Today, Burrows Cave is considered a hoax by most mainstream archeologists. The myth remains active among Iuka residents.
- "US Gazetteer files: 2010, 2000, and 1990". United States Census Bureau. 2011-02-12. Retrieved 2011-04-23.
- "2010 Census U.S. Gazetteer Files for Places – Illinois". United States Census. Retrieved 2012-10-13.
- "American FactFinder". United States Census Bureau. Retrieved 2008-01-31.
- Jack Ward. http://www.illinoiscaves.com/jackwbio.htm. Retrieved 2014-1-27. Missing or empty