Tresadern, a left-half, began his career with non-league Wanstead, moving on to Barking Town before joining West Ham United in July 1913. He was part of the West Ham side elected to the Football League in 1919 and became a regular in their league side. Tresadern made his England debut in April 1923, in the 2–2 Home International draw with Scotland, although he wasn't exactly enamoured with his performance. "I was the best player Scotland had on the field", he said. He was part of the West Ham side that lost to Bolton Wanderers in the first ever FA Cupfinal to be held at Wembley. After just two minutes Tresadern became entangled in the crowd after taking a throw-in and was unable to return to the pitch immediately. This gave Bolton's David Jack the opportunity to shoot for goal, this shot beat West Ham goalkeeper Ted Hufton to give Bolton the lead, and hit a spectator who was standing pressed against the goal net, knocking him unconscious.
In October 1924, after 279 league games for the Hammers, Tresadern moved to Burnley. He played 56 league games for Burnley before joining Northampton Town as player-manager in May 1925.
Tresadern retired from playing in December 1926 after breaking his leg. He continued as manager of Northampton until October 1930 when he became manager of Crystal Palace. In June 1935 he left Palace to manage Tottenham Hotspur, but had little success at White Hart Lane, resigning to take over at Plymouth Argyle in April 1938 rather than wait to be sacked. The war interrupted his time at Plymouth, but he remained at Home Park until November 1947.