Jacques Cohen

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Dr. Jacques Cohen
Jacques Cohen Embryologist.jpg
Born (1951-12-26) 26 December 1951 (age 62)
The Hague, Netherlands
Nationality Netherlands Dutch
Institutions University of Cambridge
Cornell University
Reprogenetics
Althea
Alma mater Erasmus University
State University of Leiden
Known for reproductive medicine
in-vitro fertilization
cryopreservation

Jacques Cohen (December 26, 1951 - ) is a Dutch embryologist living in New York, in the U.S. He is currently Director at Reprogenetics, LLC,[1][2] Laboratory Director at ART Institute of Washington at Walter Reed National Military Medical Center[3] (a joint fertility program with NIH), and Scientific Director of R & D at IVF-online. He also serves as a project coordinator at Althea.

While working with Robert G. Edwards, he was the first to freeze and successfully thaw a human blastocyst for use with in vitro fertilization[4] as the Senior Embryologist at Bourn Hall Clinic, Cambridge. At the same clinic, he developed methods to treat male factor infertility using in vitro fertilization (IVF). He was also first to co-culture human embryos with helper cells to promote growth.[5]

Dr. Cohen was one of the first to apply micromanipulation techniques to operate on eggs, sperm and embryos. Intracytoplasmic Sperm Injection (ICSI)[6] and Assisted Hatching[7] are now routinely used worldwide to aid in helping couples achieve pregnancy.[8]

He is the Senior Editor at Reproductive Biomedicine Online.[9] He has also held faculty positions at Emory University, Cornell University Medical College, and the University of Connecticut.

Early Career and education[edit]

Cohen was born in The Hague in The Netherlands. He received his B.Sc. in Biochemistry, Faculty of Biology, from the State University of Leiden. He went on to receive an M.Sc. in Reproductive Physiology from Leiden University. In 1981, he was awarded his PhD in Medicine from Erasmus University for his thesis, Interaction between human spermatozoa and hamster oocytes.[citation needed]

Embryology[edit]

In 1982, Cohen joined Bourn Hall Clinic as an Embryologist, working with Patrick Steptoe and Robert G. Edwards on techniques geared towards improving human conception through in vitro fertilization (IVF). Robert G. Edwards was the recipient of the Nobel prize for Medicine and Physiology in 2010. It was in Cambridge that Dr. Cohen first successfully froze and thawed a human blastocyst for use in IVF.[citation needed]

Dr. Cohen also pioneered the use of micromanipulation techniques that are now widespread among embryologists. He developed a precursor technique of Intracytoplasmic Sperm Injection (ICSI), which is now used for treatment of nearly all male factor infertility diagnoses. Assisted Hatching (AH) is another commonly applied technique aimed at increasing implantation rates among infertile couples. Some of his work, such as cytoplasmic transfer, an attempt to boost development using the cytoplasm of donor eggs to supplement eggs from certain infertility patients, and single sperm freezing, has caused considerable ethical debate.[10]

Dr. Cohen holds nearly a dozen patents for inventions aimed at the treatment of infertility in couples. He has published over 150 peer reviewed papers in the field and is also one of the most respected experts on embryology in the world, as he has always openly published his discoveries so others can use them to improve their patient care.

Honors and awards[edit]

References[edit]

  1. ^ Reprogenetics [1] Meet Our Team.
  2. ^ IVF.NET "Jacques Cohen - Embryo Selection" IVF.NET , 31 May 2009.
  3. ^ ART Institute of Washington - About Us [2] Jacques Cohen.
  4. ^ Cohen, Jacques; Simons, Roger F.; Edwards, Robert G.; Fehilly, Carole B.; Fishel, Simon B. (1985). "Pregnancies following the frozen storage of expanding human blastocysts". Journal of in Vitro Fertilization and Embryo Transfer 2 (2): 59–64. doi:10.1007/BF01139337. PMID 4020239. [non-primary source needed]
  5. ^ Lai, YM; Stein, DE; Soong, YK; Tang, YX; Grifo, J; Malter, HE; Talansky, BE; Cohen, J et al. (1992). "Evaluation of Vero cell co-culture system for mouse embryos in various media". Human reproduction 7 (2): 276–80. PMID 1577944. [non-primary source needed]
  6. ^ Palermo, GD; Cohen, J; Alikani, M; Adler, A; Rosenwaks, Z (1995). "Intracytoplasmic sperm injection: A novel treatment for all forms of male factor infertility". Fertility and Sterility 63 (6): 1231–40. PMID 7750593. [non-primary source needed]
  7. ^ Cohen, Jacques (1991). "Assisted hatching of human embryos". Journal of in Vitro Fertilization and Embryo Transfer 8 (4): 179–90. doi:10.1007/BF01130802. PMID 1753162. [non-primary source needed]
  8. ^ Moreno, C; Ruiz, A (1998). "Intracytoplasmic sperm injection as a routine indication in low responder patients". Human Reproduction 13 (8): 2126–2129. doi:10.1093/humrep/13.8.2126. PMID 9756282. [non-primary source needed]
  9. ^ Reproductive Biomedicine Online Journal Info - Editorial Board
  10. ^ Barritt, J. A.; Willadsen, S.; Brenner, C.; Cohen, J. (2001). "Cytoplasmic transfer in assisted reproduction". Human Reproduction Update 7 (4): 428–35. doi:10.1093/humupd/7.4.428. PMID 11476356. 

External links[edit]