Jamie Aditya is the grandson of Achdiat Karta Mihardja, Indonesia's famous writer and novelist from West Java. His mother was the daughter of Achdiat K. Mihardja mrs Natalie Widyanti and his father, Stuart Graham, is from Australia. Jamie was their third child.
He was a VJ for MTV Asia and MTV Indonesia in the 1990s. In 2000, he was chosen as the best host of Asian TV Awards and was nominated as the best host in 2003. From 2004 till 2005, he became the host of Sync or Swim, produced by Discovery Channel. In 2005, he came back to Jakarta with his wife and son and became a singer. In 2007, he was the judge of Indonesian Idol for the fourth season. He also helped indie band from Bandung, such as Rock N Roll Mafia. He duetted with Glenn Fredly in the song, "Good Times" on the album Aku Dan Wanita. He worked as a deejay in Singapore's HOTFM 91.3 radio station in September 2012, from 4 pm to 7.30 pm on weekdays, co-hosting with Charmaine Yee. He left the station that same year after a short stint.