Jan Baptist van Rensselaer (Amsterdam 18 March 1629 –Amsterdam, 24 October 1678 ) was the second son of Kiliaen van Rensselaer, and his first son by his second wife, Anna van Wely. He was the third patroon of the Manor of Rensselaerswyck and the first to visit the colony in 1651, accompanied by his brother, Jeremias. He assumed the office of director on May 8, 1652. During his residence on the estate, he lived in a style befitting his position, having brought furniture, silverware, and other personal property of much value from Holland, including portraits of the members of the van Rensselaer family.
It was Jan Baptist who placed in the Dutch Church of Beverwyck the window pane representing the van Rensselaer coat of arms in 1656. Not long afterward he returned to Holland, becoming one of the leading merchants of Amsterdam. He married Susanna van Wely and gave birth to one son, Kiliaen van Rensselaer, who lived in Holland and died without heirs.