Sixsmith took up hockey when, at the age of twelve, she was told she could no longer play for a boys' football team. She played hockey at club level for her hometown, Sutton Coldfield. As a teenager, she was selected as a reserve for the England under-18 netball team before being chosen for England's under-18 hockey squad. Jane attended St Joseph's Catholic Junior School and Bishop Walsh Catholic School.
Jane recently took part in the 2013 Maxifuels Super Sixes indoor hockey finals with her team Sutton Coldfield. They reached the final after beating Bowden Hightown in the Semi Finals. Jane scored the second goal in her teams 2-5 defeat to champions Reading HC in the final at Wembley Arena on 27 January 2013.
Sixsmith's honours include an MBE, an Olympic bronze, a European Cup gold (1991) and a Commonwealth silver medal (1998).