Janeway lesion

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Janeway lesion
Classification and external resources
ICD-10 A41.8 (ILDS A41.820)

Janeway lesions are non-tender, small erythematous or haemorrhagic macular or nodular lesions on the palms or soles only a few millimeters in diameter that are indicative of infective endocarditis.[1] Pathologically, the lesion is described to be a microabscess of the dermis with marked necrosis and inflammatory infiltrate not involving the epidermis.[1] They are caused by septic emboli which deposit bacteria, forming microabscesses.[2] Janeway lesions are distal, flat, ecchymotic, and painless.

Osler's nodes and Janeway lesions are similar, but Osler's nodes present with tenderness and are of immunologic origin.[3]

Eponym[edit]

They are named after Edward Janeway (1841-1911), a prominent American physician and pathologist who initially described the lesions.

See also[edit]

References[edit]

  1. ^ a b Farrior, J.B.; Silverman M.E. (1976). "A consideration of the differences between a Janeway's lesion and an Osler's node in infectious endocarditis". Chest. 70 (2): 239–243. doi:10.1378/chest.70.2.239. PMID 947688. 
  2. ^ Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases, 7th ed., Churchill Livingstone 2009.
  3. ^ Farrior JB, Silverman ME (August 1976). "A consideration of the differences between a Janeway's lesion and an Osler's node in infectious endocarditis". Chest 70 (2): 239–243. doi:10.1378/chest.70.2.239. PMID 947688. 

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