Janeway lesion
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Janeway lesions)
| Janeway lesion |
| Classification and external resources |
| ICD-10 |
A41.8 (ILDS A41.820) |
Janeway lesions are non-tender, small erythematous or haemorrhagic macular or nodular lesions on the palms or soles only a few millimeters in diameter that are pathognomonic of infective endocarditis.[1] Pathologically, the lesion is described to be a microabscess of the dermis with marked necrosis and inflammatory infiltrate not involving the epidermis.[1] They are caused by septic emboli which deposit bacteria, forming microabscesses.[2] Janeway lesions are distal, flat, ecchymotic, and painless.
Osler's nodes and Janeway lesions are similar, but Osler's nodes present with tenderness and are of immunologic origin.[3]
[edit] Eponym
They are named after Theodore Caldwell Janeway (1872–1917), an American professor of medicine with interests in cardiology and infectious disease.[4]
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[edit] References
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