In 1998, respondents to Chart magazine's year-end reader's poll named Arden the Canadian celebrity most deserving of her own talk show. As part of her public honesty about her family life, she has revealed that one of her brothers is serving a life sentence in prison, and that her song "Hangin' by a Thread" is dedicated to him. Arden released her ninth album, Uncover Me, on February 6, 2007. This album was her first comprising cover songs exclusively, except for one original piece, "Counterfeit Heart". This was followed by her Uncover Me Tour across Canada during the spring of 2007.
On the weekend of March 24, 2007, Arden was admitted to intensive care for heart related concerns, diagnosed as Takotsubo cardiomyopathy, a condition commonly associated with acute stress and exhaustion.
She had a 2007 USA summer tour with Michael Bublé. In 2010, they also carried the Olympic torch. She co-wrote his 2013 song "Close Your Eyes".
In September 2009, Arden released her tenth album, Free, and its first single, "A Million Miles Away," in June. She then undertook a cross-country Canadian tour, which began in November 2009. She toured with proceeds going to the "Raise-a-Reader Concert Series".
In November 2010, Arden released her first ever live CD and DVD set, entitled Spotlight. Her latest autobiography, Falling Backwards, was released on November 1, 2011, along with a second album of cover songs, Uncover Me 2. Arden's thirteenth album, Everything Almost, was released April 29, 2014 through Universal Music Canada.
Her song "Run Like Mad" was originally recorded to be the international theme song for Dawson's Creek, however it was only used for the first season. The song was used again on the DVD sets from seasons 3-6 when Paula Cole's "I Don't Want to Wait" became too expensive to license. Other songs including "Good Mother" and "You Don't Know Me" were also featured on the series.
She was a judge on season three, episode 13 entitled "Wild Rose Finale" of Top Chef Canada where she was the judge in the elimination portion of the episode.