Some or all of this article's listed sourcesmay not be reliable. Please help this article by looking for better, more reliable sources, or by checking whether the references meet the criteria for reliable sources. Unreliable citations may be challenged or deleted.(October 2014)
Reed's career includes commercial work for Time Warner, Microsoft, TiVO, Carl's Jr, Hardees, Taco Bell, Silk Soy Milk, Tanqueray, Volkswagen, Planter's Nuts and Castrol Motor Oil.  His lead role in McDonald's "The Fish Is Back" Filet-O-Fish commercial went viral in 2010. He has also featured in Remington's "Keep it Hairy" and in Muscle Milk's "The Sexy Pilgrim" music videos, both of which feature Reed as the lead role. More recently, Reed featured in a commercial for hotels.com.
Whilst at the Actors Gang theatre group, Reed would get involved with Kyle Gass and Jack Black in productions, this led him to be associated with the band Tenacious D after Gass and Black formed it in 1994.  Reed quickly became the roadie for the group and would later adopt the role of Spider-Man at their shows.  In 2000, he featured on Tenacious D's TV series in episode 5 as 'Lee' - the band's biggest fan, the episode saw the debut of the song "Lee" as well as Reed singing the song "Special Things" which he had previously performed on stage as Peter Parker at live shows.  Reed became the lead administrator for tenacious.com in 2000. In 2001, Reed went on the Tenacious D "The Rise and Fall" tour, as well as on the "Midget" tour when Tenacious D supported Weezer. In 2006, Reed starred in the film: Tenacious D in: The Pick of Destiny and also went on the world tour as "Satan" and "The Metal". Reed reprised his roles at Reading and Leeds festivals 2008, Outside Lands 2009, Bonnaroo 2010 and was most recently seen at their Blizzcon 2010 closing ceremony.
In 2002, Reed started a side-project band with Gass called Trainwreck. The band broke up in 2011. Reed also featured at "Wank" shows too in 2002.