In 2005, he switched to acting in Bollywood films and appeared in the films Shikhar (2005) and Jaan-E-Mann (2006). In 2007 he appeared in Namaste London, Om Shanti Om and the Pakistani film Mein Ek Din Laut Kay Aaoon Ga. In 2008, he played a supporting role in Jannat. His most recent film as director was Khulay Aasman Kay Neechay, a big-budget film shot in four countries (Pakistan, India, United Arab Emirates and Australia). The production failed at the box-office, resulting in a net loss of Rs. 80 million.
Sheikh's first marriage was with Zinat Mangi, a TV/film supporting actress of that era, with whom he has a daughter, Momal Sheikh and a son Shahzad. Since then Javed Sheikh has had several relationships with famous actresses like Neeli and Sana. Although it is widely assumed that he had a brief marriage with Neeli but both parties deny it. Since the divorce from Salma Agha, he is still officially single. He is the brother of Saleem Sheikh, brother-in-law of Behroze Sabzwari and uncle of Shehroz Sabzwari.