He was a student of the 'École principale du service de Santé de la Marine at Bordeaux, and during World War I served in the infantry. In 1915 he sustained war wounds, receiving the Croix de Guerre. In 1919 he defended his doctoral thesis with Contribution à la prophylaxie de la syphilis. From 1921 to 1923 he worked in a hospital at Brazzaville, Middle Congo, subsequently becoming an assistant at the Pasteur Institute in Brazzaville. Here he worked on a treatment for trypanosomiasis by testing orsanine and suramine that was developed by chemist Ernest Fourneau (1872-1949).
In 1927 he was appointed head of the laboratory at the Pasteur Institute in Saigon, and soon afterwards was transferred to Dakar, where he was promoted to medical officer of hygiene (1928). The following year he became director of the laboratory in Bamako, returning to France in 1930, where he was appointed instructor of microbiology classes at the Institut Pasteur.
In 1932 he became head of the laboratory at the Pasteur Institute in Tunis. Here he conducted tests on a vaccine against yellow fever, using a vaccine produced from the brains of mice that were infected with the yellow fever virus. In 1934, while based in Dakar, he administered the yellow fever vaccine to the populace on a large scale basis. The vaccine used in West Africa was deemed successful, its primary negative being reports of benign febrile reactions.
In 1935-37 he taught classes at Faculty of Medicine of Paris. In 1941 he is dismissed by the Vichy government, subsequently becoming a lecturer at the Faculty of Medicine of Algiers, replacing Ernest Pinoy (1873-1948). In 1945 he returned to the Pasteur Institute in Tunis, later serving as a professor of bacteriology and hygiene at the University of Strasbourg (1950-1960).
- France savantes, Prosopo (biography)
- Pasteur Institute Archives Repères chronologiques
- Time Magazine Mouse Brains v. Yellow Fever